Table 2.

Univariate Cox proportional hazard model for disease-free survival (DFS) and overall survival (OS). HR, hazard ratio; CI, confidence interval.

DFSOS
HR95% CIp-valueHR95% CIp-value
age, years
 <65
 ≥651.0090.659–1.8410.7540.9340.540–1.6440.852
AJCC stage
 I
 II1.1080.305–4.8270.8570.6670.251–2.2150.518
 III6.8232.097–22.1990.001*3.4011.184–9.7710.013*
 IV49.18512.615–191.764<0.001*40.07411.257–142.648<0.001*
differentiation
 high
 moderate1.3150.750–2.3560.3411.4580.764–2.7800.453
 low3.5771.885–6.786<0.001*4.3582.140–8.872<0.001*
vascular invasion
 yes4.9012.469–9.731<0.001*4.6882.152–9.937<0.001*
 no
IL-38 expression
 positive
 weak2.5281.194–5.6730.011*2.1470.882–5.1260.152
 negative6.1783.054–12.462<0.001*6.3882.875–14.014<0.001*
  • *p < 0.05 indicates a significant association among the variables.