Table 2.

Top five proteins with increased abundance in A. fumigatus ΔgliT::ΔgtmA compared with ΔgliT following a 3 h exposure to gliotoxin (2.5 µg ml−1). Data sorted by fold change, in descending order.

protein descriptionlog2(fold increase)peptidessequence coverage (%)protein IDs
glutathione S-transferase encoded in the gliotoxin biosynthetic gene cluster, GliG4.128731061.2AFUA_6G09690
N methyltransferase, encoded in the putative gliotoxin biosynthetic gene cluster, GliN3.024831989AFUA_6G09720
conserved hypothetical protein, encoded in the putative gliotoxin biosynthetic gene cluster, GliH2.86394530.7AFUA_6G09745
predicted O-methyltransferase, encoded in the putative gliotoxin biosynthetic gene cluster, GliM2.786122376.1AFUA_6G09680
glutamyl-tRNA(Gln) amidotransferase, subunit A2.16436615.9AFUB_092380
D-3-phosphoglycerate dehydrogenase, role in l-serine biosynthetic process2.146921334.2AFUA_2G04490